Effect of Natural Antibacterial Mouthwash on Taste, Salivary pH and Bacteria in High Caries Risk pt
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Evaluate the effect of propolis extract mouthwash and pomegranate extract mouthwash on taste alteration, salivary pH and antibacterial activity against streptococcus mutans in high caries risk patients.
Full description
This study will be carried out to evaluate and compare the effect of propolis extract mouthwash and pomegranate (botanical name: Punica granatum) extract mouthwash on taste alteration, salivary pH and antibacterial activity against streptococcus mutans in high caries risk patients.
Thats by taking unstimulated saliva samples at the morning before using the mouthwash, then taking another one after using the mouthwash and finally after 7 days, to make a bacterial culture and measure the salivary pH by a digital pH meter and evaluate taste changes by a questionnaire.
Enrollment
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Inclusion criteria
- High caries risk patients defined according to American Dental Association (ADA)
- Systematically healthy
- Not taking any medication interfering with saliva secretion
- Subjects who signed informed consent
- Age range from 17-50 years
Exclusion criteria
- Subjects suffering from any medical or systematic disease
- Smokers
- Pregnant females
- Allergy to any of the mouthwash ingredients
- Patients older than 50 years
Trial design
Primary purpose
Allocation
Interventional model
Masking
80 participants in 4 patient groups, including a placebo group
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Data sourced from clinicaltrials.gov
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