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Effect of Nd-YAG Laser on Hypertrophic Scar

Cairo University (CU) logo

Cairo University (CU)

Status

Completed

Conditions

Hypertrophic Scar

Treatments

Procedure: Nd- YAG laser at 532nm wavelength

Study type

Interventional

Funder types

Other

Identifiers

NCT06347081
P.T.REC/012/00449

Details and patient eligibility

About

A hypertrophic scar is a serious health concern in the industrialized world. Two groups of patients were treated with standard medical care. The experimental group received additional laser therapy. scar assessment was measured immediately before treatment, after 3, and 7 months.

T test for comparison before-treatment between the control and study groups. ANOVA with repeated measures test for comparison among other measures.

Full description

Background: A hypertrophic scar is a serious health concern in the industrialized world. Objective: The impact of this study was to investigate the effect of the Nd-YAG laser at 532nm wavelength on hypertrophic scars. Patients and methods: Forty male and female patients with hypertrophic scars, ranging in age from fifteen to forty-five, were recruited from the burn patients' clinic within the Faculty of Physical Therapy, Cairo University, for this study. They were randomized into two equivalent groups. Group A (the control group) consisted of 20 patients who were given standard medical care, nursing, physiotherapy, and a sham laser during the course of treatment. In contrast, Group B (the study group) consisted of 20 patients who were given 532 nm laser radiation in addition to standard medical care, nursing, and physiotherapy. Treatment was conducted every 2 weeks for 14 sessions. Outcome measures included Vancouver Scar Scale score and scar volume. The assessment procedures were applied before the initiation of treatment (Pre), after 3 months (Post1) and after 7 months (Post 2) from the beginning of the treatment.

Enrollment

40 patients

Sex

All

Ages

30 to 50 years old

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

IInclusion Criteria:

• Adult patients with hypertrophic scars.

Exclusion Criteria:

  • Patients were excluded if they had taken oral retinoids in the last year.
  • Patients had any skin defects.
  • Patients had any history of photosensitivity.
  • Patients experienced active skin diseases in the treatment regions (such as psoriasis, cancer, or autoimmune disease).

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

40 participants in 2 patient groups, including a placebo group

Placebo
Placebo Comparator group
Description:
Patients received standard medical care, nursing, physiotherapy, and a sham laser during the course of treatment
Treatment:
Procedure: Nd- YAG laser at 532nm wavelength
Laser group
Active Comparator group
Description:
Patients received 532 nm laser radiation in addition to standard medical care, nursing, and physiotherapy.
Treatment:
Procedure: Nd- YAG laser at 532nm wavelength

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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