Effect of Nefazodone on Relapse in Females With Cocaine Abuse - 10

National Institutes of Health (NIH)

Status and phase: Completed; Phase 3

Conditions: Cocaine-Related Disorders

Treatments: Drug: Nefazodone

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT00000293

P50-09259-10

NIDA-09259-10

Details and patient eligibility

About

The purpose of this study is to determine the effect of nefazodone on relapse to cocaine use in depressed and non-depressed females with cocaine abuse/dependence.

Full description

The purpose of this study is to determine the effect of nefazodone on relapse to cocaine in women and if a greater effect will be seen in the dependent condition. A relapse and coping skills questionnaire will be utilized to determine the various factors important to the relapse process.

Sex: Female

Ages: 18 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Female, ages 18-55, cocaine abuse/dependence, use of cocaine 7 days of the last 30 days or of the 30 days prior to current abstinence, less than 90 days current abstinence, at least an 8th grade education.

Exclusion criteria

Unstable medical conditions; current use of Hismanal, Seldane, or Propulsid; dx of MR, OBS, bipolar, schizophrenia.