Effect of Neural Mobilization on Lumbosacral Radiculopathy Patients With Peripheral Sensitization

Mohammed Al-Ghamdi

Status: Completed

Conditions: Radiculopathy

Treatments: Other: Transcutaneous Electrical Nerve Stimulation (TENS); Other: Neural mobilization exercises -Slider technique; Other: Neural mobilization exercises -Tensioner technique

Study type: Interventional

Funder types: Other

Identifiers

NCT03621878

IRB-2014-04-321

Details and patient eligibility

About

The primary purpose of this study was to investigate the effects of slider and tensioner techniques on pain, hip and knee ROM in lumbosacral radiculopathy patients with peripheral sensitization. A secondary purpose was to evaluate the correlation between these outcomes measurements.

Full description

Study design: Double-blind case-control trial. Methods: Fifty-one male lumbosacral radiculopathy patients with peripheral sensitization, were divided into one of the three groups: slider, tensioner, and control. The primary outcome measurements were visual analog scale (VAS) for pain, hip range of motion (ROM) during SLR test, and knee flexion ROM during slump test. The measurements were taken at baseline, after 1st, 3rd, and 6th session.

Statistical Analysis: A two-way mixed design analysis of variance (MANOVA) with post-hoc (Bonferonni Correction) was used to calculate the differences with Time (baseline, 1st,3rd,6th sessions) as a within-group factor and Group (control, slider, and tensioner) as a between-group factor. The effect size was calculated with Cohen's d. Pearson's correlation was used for correlation analysis.

Enrollment: 51 patients

Sex: Male

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with lumbosacral radiculopathy with dominant peripheral sensitization
• patients with unilateral leg pain.
• patient S-LANSS score > 12,
• negative sensory and motor examination.
• positive neural tissue provocation tests (straight leg raising test, slump test).
• adult.
• pain duration of more than 3 months.

Exclusion criteria

• S-LANSS score ≥ 12,
• motor or sensory deficits,
• history of back or lower extremity surgeries,
• bilateral referred pain,
• patients with pacemakers, cardiovascular problems, epilepsy, active malignancy, dermatological conditions, and diminished pain sensation.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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51 participants in 3 patient groups

Control group

Active Comparator group

Description:

Patients in this group had 6 sessions in 2 weeks of Transcutaneous Electric Nerve Stimulation (TENS).

Treatment:

Other: Transcutaneous Electrical Nerve Stimulation (TENS)

Tensioner Group

Experimental group

Description:

Patients in this group had 6 sessions in 2 weeks of TENS combined with neural mobilization exercises (Tensioner technique).

Treatment:

Other: Neural mobilization exercises -Tensioner technique

Slider Group

Experimental group

Description:

Patients in this group had 6 sessions in 2 weeks of TENS combined with neural mobilization exercises (Slider technique).

Treatment:

Other: Neural mobilization exercises -Slider technique