Effect of Non-alcoholic Fatty Liver Disease on Kidney Functions

Assiut University

Status: Unknown

Conditions: Liver Diseases

Treatments: Diagnostic Test: glomerular filtration rate

Study type: Observational

Funder types: Other

Identifiers

NCT03172650

NAFLD

Details and patient eligibility

About

Non-alcoholic fatty liver disease is the most common cause of chronic liver disease worldwide. It is defined as the accumulation of fat (>5%) in the liver cells in the absence of excessive alcohol intake or other causes of liver disease including viral, drug-induced, or autoimmune. Non-alcoholic fatty liver disease is a hepatic manifestation of metabolic syndrome.

Enrollment: 120 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All non alcoholic fatty liver disease patients evidenced by abdominal ultrasound.
• Urine analysis whether normal or renal sedimentation.

Exclusion criteria

1. Alcoholic fatty liver patients.
2. patients known to have diabetes mellitus.
3. patients with other causes of liver disease as viral hepatitis, drug induced,or autoimmune.
4. patients known to have kidney disease.
5. Hypertension.
6. Hyperuricemia.
7. Impaired urea and creatinine patients.

Trial design

120 participants in 2 patient groups

study group

Description:

non alcoholic fatty liver disease patients

Treatment:

Diagnostic Test: glomerular filtration rate

Control group

Description:

fatty liver patients

Treatment:

Diagnostic Test: glomerular filtration rate