Effect of Nutritional Intervention on the Lipid Profile of HIV-Positive Patients Who Start HAART: a Randomized Trial

Hospital de Clinicas de Porto Alegre

Status: Completed

Conditions: HIV Infections

Treatments: Behavioral: Nutritional

Study type: Interventional

Funder types: Other

Identifiers

NCT00429845

HCPA2004-012

Details and patient eligibility

About

Highly active antiretroviral therapy (HAART) in HIV-positive patients is associated with the development of dyslipidemia, a risk factor for cardiovascular events. The objective of this study was to evaluate the effect of dietary intervention in individuals who start HAART.

Full description

Adult patients prescribed to HAART that met the exclusion criteria were consecutively enrolled in a randomized trial:

• control (receiving general guidelines on dietary education)
• intervention (receiving general guidelines on dietary education and nutritional follow-up every 3 months)

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• HIV-positive individuals naive to HAART, with clinical indication to start therapy

Exclusion criteria

• Diabetes Mellitus
• Pregnancy
• Active opportunistic disease
• Any mental deficiency
• Use of lipid profile influencing drugs
• Use of illicit drugs

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)