Effect of Oliceridine on Rebound Pain

Xiamen University

Status: Enrolling

Conditions: Oliceridine; Arthroscopic Knee Surgery; Rebound Pain

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT06382896

FirstAHXiamenU-YB-2

Details and patient eligibility

About

The purpose of this clinical study was to identify the risk factors for postoperative pain outburst in patients undergoing arthroscopic knee surgery after Oliceridine and nerve block, and to evaluate the effect of oxeridine on early rehabilitation exercise in patients. A total of 320 patients undergoing arthroscopic knee arthroscopy under general anesthesia combined with femoral nerve block were selected to record the time and duration of postoperative pain outbreak, pain degree, age, gender, operation type, previous surgical history and other related risk factors.

Enrollment: 320 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age 18-70 years old;2. Body mass index (BMI) 18-30kg /m2;3. American Society of Anesthesiologists (ASA) Grade I to II;4. Hospital stay >24h.

Exclusion criteria

1. Patients who cannot understand the numerical rating scale score and give feedback;2. Known allergy to the drug in the study;3. Infection of puncture site with nerve block;4. Oral analgesics for more than 2 weeks before surgery;5. Long-term use of glucocorticoids;6. Simultaneous surgery on both limbs;7. A psychopath;8. Severe compound trauma;9. Pregnant and lactating women.

Trial design

320 participants in 1 patient group

Patients undergoing ambulatory arthroscopic knee surgery

Treatment:

Other: No intervention