Effect of One-time Versus Three-times of Umbilical Cord Milking on Neonatal Hemoglobin in Late Preterm (RRT)

Queen Savang Vadhana Memorial Hospital, Thailand

Status: Completed

Conditions: Umbilical Cord Milking

Treatments: Other: three-times umbilical cord milking; Other: one-time umbilical cord milking

Study type: Interventional

Funder types: Other

Identifiers

NCT05551390

010/2564

Details and patient eligibility

About

To compare the neonatal hemoglobin (Hb) in late preterm between one-time versus three-times of umbilical cord milking (UCM)

Full description

This was a double-blind randomized controlled trial that performed between May 2021 to March 2022 at the Obstetrics and Gynecology Department of Queen Savang Vadhana Memorial Hospital. Late preterm pregnant women (34-36+6 week's gestation) that exclude placenta accrete/percreta, placenta previa, placental abruption, congenital anomaly and hydrops fetalis, were randomized in a 1:1 ratio to either one-time or three-times UCM. The primary outcome was neonatal Hb level at 48-72 hour after birth.

Enrollment: 162 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Late preterm pregnant women (34-36+6 week's gestation)

Exclusion criteria

• placenta accrete
• placenta percreta
• placenta previa
• placental abruption
• congenital anomaly
• hydrops fetalis

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Sequential Assignment

Masking: None (Open label)

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162 participants in 2 patient groups

one-time umbilical cord milking

Experimental group

Description:

Before UCM procedures, in the case of vaginal delivery, the maternity doctor or nurse held the newborn below the level of the introitus. In the case of a cesarean section, the surgeon carries the newborn below the level of the incision. Then maternity nurse or doctor swiped blood in length 20 centimeters of umbilical cord into the newborn, according to the number of swipes that assigned, then cutting the umbilical cord by the international standard methods. Newborns after birth were cared for and assessed according to the newborn nursing standards of QSMH in the department of pediatrics.

Treatment:

Other: one-time umbilical cord milking

three-time umbilical cord milking

Experimental group

Description:

Before UCM procedures, in the case of vaginal delivery, the maternity doctor or nurse held the newborn below the level of the introitus. In the case of a cesarean section, the surgeon carries the newborn below the level of the incision. Then maternity nurse or doctor swiped blood in length 20 centimeters of umbilical cord into the newborn, according to the number of swipes that assigned, then cutting the umbilical cord by the international standard methods. Newborns after birth were cared for and assessed according to the newborn nursing standards of QSMH in the department of pediatrics.

Treatment:

Other: three-times umbilical cord milking