Effect of Oral Feeding on Patients With Chronic Obstructive Pulmonary Disease

Chao Phya Abhaibhubejhr Hospital

Status: Not yet enrolling

Conditions: Chronic Obstructive Pulmonary Disease

Treatments: Device: Nasogastric Tube Feeding; Device: Oral Tube Feeding; Behavioral: Basic treatment

Study type: Interventional

Funder types: Other

Identifiers

NCT06505876

Oral feeing-COPD

Details and patient eligibility

About

This is a prospective, randomized controlled clinical trail that involved patients with Chronic Obstructive Pulmonary Disease.The goal of this clinical trial is to compare the clinical effect of Oral Tubes vs Nasogastric Tubes in patients with Chronic Obstructive Pulmonary Disease. The main questions it aims to answer are:

Compared to Nasogastric Tube Feeding, can the Oral esophageal Tube Feeding better improve the nutritional status and pulmonary infection

Full description

This is a prospective, randomized controlled clinical trail that involved patients with Chronic Obstructive Pulmonary Disease.The goal of this clinical trial is to compare the clinical effect of Oral Tubes vs Nasogastric Tubes in patients with Chronic Obstructive Pulmonary Disease. The main questions it aims to answer are:

Compared to Nasogastric Tube Feeding, can the Oral esophageal Tube Feeding better improve the nutritional status and pulmonary infection

Participants will be divided into two groups randomly, with different nutritional support respectively.

Enrollment: 80 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• A diagnosis of COPD confirmed by spirometry
• ≥18 years of age
• Sinus rhythm ≥50/min and < 120/min at inclusion
• Written informed consent

Exclusion criteria

• Known hypersensitivity to metoprolol or related derivatives
• Sinus bradycardia (resting heart rate < 50/min)
• Sick sinus syndrome unless treated with a pacemaker
• Atrial fibrillation/flutter
• Clinical signs or previous diagnosis of heart failure, angina pectoris, myocardial infarction, cerebrovascular disease, or critical peripheral ischemia

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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80 participants in 2 patient groups

Oral Tube Feeding+Basic treatment

Experimental group

Description:

The patients were provided with 1) basic treatment including intracranial pressure reduction, anti-infection therapy, blood pressure and blood glucose control. For the observation group, the nasogastric tube was removed, and Intermittent oro-esophageal tube feeding was initiated for nutrition support within 4 hours after completing the admission assessment, following the standard Intermittent oro-esophageal tube feeding procedure.

Treatment:

Behavioral: Basic treatment

Device: Oral Tube Feeding

Nasogastric Tube Feeding+Basic treatment

Active Comparator group

Description:

The patients were provided with 1) basic treatment including intracranial pressure reduction, anti-infection therapy, blood pressure and blood glucose control. Patients in the control group were provided with nutrition support by the indwelling nasogastric tube. The entire feeding process strictly followed the standardized procedure for nasogastric feeding.

Treatment:

Behavioral: Basic treatment

Device: Nasogastric Tube Feeding