Effect of Oral L-carnitine Supplement on Lipid Profile, Anemia, and Quality of Life of Patients

Isfahan University of Medical Sciences

Status and phase

Completed

Phase 2

Conditions

Complication of Hemodialysis

Treatments

Drug: L-carnitine

Drug: placebo

Study type

Interventional

Funder types

Other

Identifiers

NCT01278693

ASD-1213-11

Details and patient eligibility

About

The purpose of this study is to determine Effect of oral L-carnitine supplement on lipid profile, anemia, and quality of life.

Full description

In patients under maintenance hemodialysis several factors reduce the body stored carnitine which in turn affected dyslipidemia, anemia, and general health in these patients. The investigators evaluated the effect of oral L-carnitine supplementation on lipid profiles, anemia, and quality of life in hemodialysis patients.

Enrollment

54 patients

Sex

Female

Ages

18 to 75 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

being in the age range of 18-75 having the history of at least 12 weeks of hemodialysis and at least three times a week and each session almost for four hours having serum triglyceride or total cholesterol concentration >200 mg/dl or serum HDL concentration >40 mg/dl in the beginning of the study.

Exclusion criteria

taking carnitine supplement or the drug that interact with carnation lowering the seizure threshold in the last month being affected by liver function abnormalities, hypothyroidism, chronic infectious diseases (such as hepatitis), inflammatory diseases, CNS mass having the history of seizure.