ClinicalTrials.Veeva

Menu

Effect of Paravertebral Muscle Fat Infiltration on Rocuronium Use in Lumbar Surgery (RUILS)

Z

Zheng Guo

Status and phase

Completed
Early Phase 1

Conditions

Spinal Stenosis Lumbar

Treatments

Drug: Rocuronium Bromide

Study type

Interventional

Funder types

Other

Identifiers

NCT05619848
yuewei20221109

Details and patient eligibility

About

To investigate the effect of different degrees of fat infiltration on rocuronium use in lumbar surgery was monitored by trapezius muscle relaxation.

Full description

Select the patients who will receive posterior lumbar surgery in the Second Hospital of Shanxi Medical University. According to the classification criteria of fat infiltration, it will be divided into three groups: mild, moderate and severe. This study will pump and titrate rocuronium bromide under the monitoring of muscle relaxation during the operation, record the dosage of rocuronium bromide and the duration of pump injection, and evaluate its clinical effect. Postoperative results include the use and clinical effect of rocuronium, which will be counted after the trial.

Enrollment

87 patients

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age: 18-65; ASA grade I-II; no significant cardiopulmonary disease; no history of surgery in the corresponding surgical area; no coagulopathy.

Exclusion criteria

refusal to participate by the present experimenter; those with severe cardio-cerebrovascular disease, severe hepatic and renal dysfunction; taking medications affecting the neuromuscular junction; area of monitoring site for skin breakers; patients with intraoperative bleeding, anaphylactic shock, or other serious complications; patients requiring intraoperative neurophysiological monitoring (including sensory, motor evoked potentials).

Trial design

Primary purpose

Other

Allocation

Non-Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

87 participants in 3 patient groups

Mild fat infiltration
Experimental group
Description:
Fat infiltration rate is less than 30%
Treatment:
Drug: Rocuronium Bromide
Moderate fat infiltration
Experimental group
Description:
Fat infiltration rate is 30%\~50%
Treatment:
Drug: Rocuronium Bromide
Server fat infiltration
Experimental group
Description:
Fat infiltration rate is greater than 50%
Treatment:
Drug: Rocuronium Bromide

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems