Effect of Passive Smoking on Oxidative Stress and Dental Caries in Children

Merve Erkmen Almaz

Status: Completed

Conditions: Dental Caries; Passive Smoking; Oxidative Stress

Treatments: Diagnostic Test: taking saliva samples to determine oxidative stress markers TAS and TOS

Study type: Observational

Funder types: Other

Identifiers

NCT04298996

2016-140

Details and patient eligibility

About

The purpose of the present study was to determine the effect of passive smoking on oxidative stress and dental caries in children.A total of 180 children were included to the study as follows; 90 children exposed to passive smoking, and 90 children in the control group (unexposed controls). Also demographic data were recorded (age, gender, parental education levels, child's tooth-brushing habit and child's daily dietary sugar exposure, family income). Dental examination of children were performed and caries prevalence of the patients were recorded. Unstimulated saliva samples were collected from children. Saliva 'cotinine levels' and oxidative stress markers 'total antioxidant status' (TAS), and' total oxidant status' (TOS) were evaluated by using Enzyme-linked immunosorbent assay (ELISA). The obtained data parameters of the two groups were evaluated and comparison was performed.

Enrollment: 180 patients

Sex: All

Ages: 6 to 12 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

-Systemically healthy children

Exclusion criteria

• Uncooperative children
• The presence of orthodontic/intraoral appliance
• Any disease or condition known to affect oxidative stress

Trial design

180 participants in 2 patient groups

study group (passive smoking children)

Description:

examining for caries prevalence and taking saliva samples to determine oxidative stress markers TAS and TOS

Treatment:

Diagnostic Test: taking saliva samples to determine oxidative stress markers TAS and TOS

control group

Description:

examining for caries prevalence and taking saliva samples to determine oxidative stress markers TAS and TOS

Treatment:

Diagnostic Test: taking saliva samples to determine oxidative stress markers TAS and TOS