Effect of Patient Position on Arterial, End-tidal and Transcutaneous Carbon Dioxide

Seoul National University

Status: Unknown

Conditions: Ventilation Perfusion Mismatch

Treatments: Other: Arterial carbon dioxide monitoring; Other: End-tidal carbon dioxide monitoring; Other: Transcutaneous carbon dioxide monitoring

Study type: Interventional

Funder types: Other

Identifiers

NCT03508791

201804-1

Details and patient eligibility

About

Investigators evaluate the effect of patient position (Trendelenburg and reverse Trendelenburg) on arterial, end-tidal and transcutaneous carbon dioxide partial pressure in patients undergoing laparoscopic surgery.

Full description

Investigators evaluate the effect of patient position (Trendelenburg and reverse Trendelenburg) on arterial, end-tidal and transcutaneous carbon dioxide partial pressure in patients undergoing laparoscopic surgery. Arterial carbon dioxide partial pressure is assessed intermittently before, during, and after pneumoperitoneum. End-tidal and transcutaneous carbon dioxide partial pressure are continuously monitored.

Enrollment: 142 estimated patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult patients undergoing laparoscopic surgery (expected duration of pneumoperitoneum > 1 hour) in the Trendelenburg or reverse Trendelenburg positions

Exclusion criteria

• hemodynamically unstable patients due to decompensated heart failure, sepsis, or symptomatic arrhythmia, etc.
• symptomatic pulmonary disease, chronic obstructive pulmonary disease

Trial design

Primary purpose: Other

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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142 participants in 2 patient groups

Trendelenburg group

Active Comparator group

Description:

Arterial, end-tidal, and transcutaneous carbon dioxide partial pressure are monitored in the Trendelenberg position

Treatment:

Other: Transcutaneous carbon dioxide monitoring

Other: End-tidal carbon dioxide monitoring

Other: Arterial carbon dioxide monitoring

reverse Trendelenburg group

Active Comparator group

Description:

Arterial, end-tidal, and transcutaneous carbon dioxide partial pressure are monitored in the reverse Trendelenberg position

Treatment:

Other: Transcutaneous carbon dioxide monitoring

Other: End-tidal carbon dioxide monitoring

Other: Arterial carbon dioxide monitoring