Effect of Percutaneous Botulinum Toxin A Injection on Natural Course of Upper Lid Retraction in Thyroid Eye Disease

Shahid Beheshti University of Medical Sciences

Status and phase: Unknown; Phase 3; Phase 2

Conditions: Eye Diseases

Treatments: Drug: Botulinum toxin A injection

Study type: Interventional

Funder types: Other

Identifiers

NCT00370734

8375

Details and patient eligibility

About

In active phase of thyroid eye disease some patients have obvious upper lid retraction , and sometimes exposure keratopathy .To date there is not any standard treatment for this situation . We are going to compare the natural course of the upper lid retraction with injection of botulinum toxin A injection to upper lid percutaneously.

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• all the patients wiht oper lid retraction in active phase of thyroid ophthalmopathy

Exclusion criteria

• patients in non active phase

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)