Effect of Periodontal Therapy in the Systemic Status of Individuals With Chronic Periodontitis and Diabetes Type 2

University of Brasilia

Status: Terminated

Conditions: Chronic Periodontitis; Diabetes Type 2

Treatments: Procedure: nonsurgical periodontal therapy; Device: Mechanical periodontal therapy

Study type: Observational

Funder types: Other

Identifiers

NCT02589314

CAAE 46609515.7.0000.0030

Details and patient eligibility

About

This study will evaluate if periodontal mechanical treatment is capable to alter immunological and genetical parameters related to systemic health in patients with chronic periodontitis ant diabetes type 2.

Enrollment: 90 patients

Sex: All

Ages: 30 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Periodontitis group:

• Minimum of 15 teeh;
• At least 30% of sites with periodontal probing depth ≥ 4 mm and at least two teeth with CAL ≥ 3 mm; Age ≥30 years;

Control group:

• Systemically healthy;
• 20 teeth;
• Probing depth ≤3 mm, clinical attachment level ≤3 mm , ≤10% of sites with bleeding on probing.

Exclusion criteria

• Periodontal treatment in the last six months;
• Continued use of medications such as antibiotics, immunomodulatory, anti-inflammatory drugs or corticosteroids in the last three months;
• Systemic diseases that interfere with periodontal condition, except for diabetes for the test group (HIV, cancer, immune disorders, acute infections, severe allergies, gastrointestinal or kidney disease, morbid obesity [BMI 40 kg / m2] or underweight [evil nourished BMI <18.5 kg / m2], etc.); Pregnant or lactating; smoking; Age <30 years; Indigenous groups.

Trial design

90 participants in 1 patient group

root planning

Treatment:

Procedure: nonsurgical periodontal therapy

Device: Mechanical periodontal therapy