Effect of Periodontal Treatment on Salivary Biomarkers

Baruch Padeh Medical Center

Status: Unknown

Conditions: Chronic Periodontitis

Treatments: Procedure: periodontal treatment - scaling and root planning

Study type: Interventional

Funder types: Other

Identifiers

NCT02159781

2013-1476.CTIL

Details and patient eligibility

About

The investigators plan to recruit 40 healthy patients referred to the unit of Periodontology, diagnosed with generalized moderate - severe chronic periodontitis.

treatment will include 4 - 6 sessions of scaling + root planning, oral hygiene instructions and motivation.

Whole saliva will be collected at intake and 8 - 14 weeks post periodontal treatment.

Saliva will be analyzed for trans locator protein. Study hypothesis: Periodontal treatment has an affect on saliva components.

Enrollment: 60 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy patients
• moderate - sever chronic periodontitis

Exclusion criteria

• systemic disease
• pregnancy
• subjects under the age of 18

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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60 participants in 1 patient group

periodontal treatmnent

Experimental group

Treatment:

Procedure: periodontal treatment - scaling and root planning