Effect of Perioperative Factors on the Analgesia Nociception Index (ANIFACT)

Caen University Hospital

Status: Unknown

Conditions: Intraoperative Neurophysiological Monitoring

Study type: Observational

Funder types: Other

Identifiers

NCT02305576

13-181

Details and patient eligibility

About

The Analgesia Nociception Index (ANI) is a new unitless marker derived from Heart Rate Variability spectral analysis, ranging between 0 and 100 and expressing the parasympathetic tone. The ANI is proposed as surrogate marker for the analgesia nociception balance. However, many perioperative factors such as medications, position, maneuvers may influence the ANI values and may lead to misinterpretation. Moreover the ability of the ANI to guide opioid dosing has never been tested. Therefore, the aim of our study is to collect in a database all the perioperative factors and to study their influence on the ANI.

Enrollment: 600 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing scheduled surgery

Exclusion criteria

• Non sinusal rhythm
• Pace maker or defibrillator holders
• Pregnancy or feeding
• American Society of Anesthesiology physical status 4