Effect of Pertubation on Pregnancy Rates Before Intrauterine Insemination Treatment

Gazi University

Status and phase: Completed; Phase 2

Conditions: Insemination; Infertility; Pertubation

Treatments: Procedure: Pertubation

Study type: Interventional

Funder types: Other

Identifiers

NCT01999959

3061750

Details and patient eligibility

About

To demonstrate a possible beneficial impact of pertubation we designed a randomized prospective study, in which uterine washing was administered prior to insemination in patients diagnosed with unexplained infertility.

Enrollment: 180 patients

Sex: Female

Ages: 18 to 44 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age of 18-44 years; presence of regular menstrual cycles and ovulation; absence of tubal occlusion on HSG; sperm concentration >15 million spermatozoa/ml and total sperm number >39 million/ml according to WHO criteria

Exclusion criteria

• the presence of endocrinologic disease; use of nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids; clinical findings suggestive of pelvic inflammatory disease; and the presence of undiagnosed uterine bleeding

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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180 participants in 2 patient groups

Pertubation performed

Experimental group

Description:

Study group had pertubation and insemination

Treatment:

Procedure: Pertubation

Pertubation not performed

No Intervention group

Description:

Study group had insemination only