Effect of Petrolatum Coating on Fast-absorbing Gut Suture

San Antonio Uniformed Services Health Education Consortium

Status: Completed

Conditions: Dermatology; Mohs Micrographic Surgery; Suture; Suture Techniques; Absorbable, Coated Sutures; Suture Dermatologic; Closure Technique

Treatments: Device: Petrolatum coating of fast-absorbing gut suture

Study type: Interventional

Funder types: Other U.S. Federal agency

Identifiers

NCT07127029

FWH20160040H

Details and patient eligibility

About

This study is designed to evaluate the effect of using petrolatum to coat gut suture. This coating is commonly performed to make the suture more easy to handle; however, it was unknown if it affects the absorption rate of the suture. Two gut sutures were placed into the skin of 14 healthy volunteers and randomized between coated and uncoated with petrolatum. Participants self-reported the time to resorption. The study concluded that there was no significant effect to the application of petrolatum, and reinforced that the gut sutures are a natural product with some inherent variability to their absorption.

Enrollment: 14 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy volunteers within department of Dermatology
• Able to receive care within the host facility (Dept of Defense)

Exclusion criteria

• current or planned pregnancy
• Allergy to lidocaine
• Infection on the shoulder site

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Single Blind

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14 participants in 1 patient group

6-0 Fast-Absorbing Gut Suture

Experimental group

Description:

Two 6-0 fast-absorbing gut sutures were placed in the skin of deltoid, randomized to site A/B for the control (uncoated) and intervention (petrolatum coated) suture.

Treatment:

Device: Petrolatum coating of fast-absorbing gut suture