Effect of Photobiostimulation Versus Pulsed Electromagnetic Field on Quality of Life in Adults With Chronic Rhinosinusitis

Cairo University (CU)

Status: Enrolling

Conditions: Low Level Laser Therapy; Quality of Life; Pulsed Electromagnetic Filed; Photobiostimulation; Chronic Rhinosinusitis (Diagnosis)

Treatments: Device: pulsed electromagnetic therapy; Other: Self-sinus massage technique; Device: Photobiostimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT06986629

Samar-005562

Details and patient eligibility

About

This study was done to find out the effect of photobiostimulation and pulsed electromagnetic field in patients with chronic rhinosinusitis on:

• Quality of life.
• Pulmonary function.
• Mean platelet volume.
• headache .
• total nasal symptoms.

Full description

Chronic rhinosinusitis is a severe disease that significantly impacts a patient's quality of life, leading to significant economic impacts on healthcare resources and absenteeism. Symptoms interfere with daily activities and can lead to medication resistance. Treatment options like steroids, oral antibiotics, and sinus surgery are less effective, and disease recurrence remains high even after surgery. Alternative therapies like low-level laser therapy and pulsed electromagnetic filed have shown promise in improving symptoms and potentially making low-level laser therapy a non-invasive treatment for Chronic rhinosinusitis

Enrollment: 60 estimated patients

Sex: All

Ages: 20 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Participants suffering from mild to moderate symptoms (baseline Total nasal symptoms score ≤ 9).
2. Subjects age range from 20 to 40 years old.
3. Patients of both sexes.
4. proven positive allergy test (skin prick test or multiple allergen simultaneous test) to any of the common perennial allergens such as dust mites, molds, insects, and animal dander within the last 12 months

Exclusion criteria

• Pregnant or breastfeeding women.
• Patients with a definite deviated nasal septum, or history of operation within the last 6 months.
• Hypertension, diabetes mellitus, malignancy, active pulmonary tuberculosis, active respiratory disease like asthma, or other systemic diseases.
• Long-term use of corticosteroids or immunosuppressive agents.
• Participation in another clinical study within 30 days.
• Hyperthyroidism
• Patients who had used antihistamines within 1 week, topical corticosteroids within 2 weeks, systemic corticosteroids within 4 weeks, anticholinergic drugs within 3 days, antileukotriene drugs within 1 week, decongestants within 3 days, tricyclic antidepressants or phenothiazines within 2 weeks, nonsteroidal analgesics within 2 weeks, and other drugs that the researchers believed were inappropriate.
• Patients with Tattoos, moles and dark skin

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 3 patient groups

pulsed electromagnetic therapy

Experimental group

Description:

This group included twenty adults with chronic rhinosinusitis and received pulsed electromagnetic therapy. This treatment protocol will be carried out three times per week for 8 weeks

Treatment:

Device: pulsed electromagnetic therapy

Photobiostimulation

Active Comparator group

Description:

This group included twenty adults with chronic rhinosinusitis and received low level laser therapy. This treatment protocol will be carried out three times per week for 8 weeks

Treatment:

Device: Photobiostimulation

Self-sinus massage technique

Active Comparator group

Description:

This group included twenty adults with chronic rhinosinusitis and received the self-sinus massage technique only. This treatment protocol will be carried out three times per week for 8 weeks

Treatment:

Other: Self-sinus massage technique