Effect of Physical Activity Intervention on Overweight and Obese Patients With Endometrial Cancer

Peking University

Status: Completed

Conditions: Physical Activity; Endometrium Cancer; Weight Management

Treatments: Behavioral: Physical activity

Study type: Interventional

Funder types: Other

Identifiers

NCT06312917

2023PHB183

Details and patient eligibility

About

This study evaluated the clinical outcome of exercise management on patients with endometrial cancer treated with fertility preservation, including the effect of complete response rate, complete response time, recurrence rate, recurrence time, etc., and physical composition, to evaluate the effectiveness of physical activity on weight management.

Enrollment: 72 patients

Sex: Female

Ages: 20 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Participants were patients who met the following predefined eligibility criteria: Ages 20-40; Overweight or obese; The pathological diagnosis was EC (endometrioid, grade I, no myometrium invasion or metastasis). Not pregnant; Be willing to comply with test requirements after being fully informed of all risks and inconveniences associated with the test.

Exclusion criteria

• Recurrent or metastatic disease; Currently participating in regular exercise at least 2 days per week; Pregnant at the start of the study; Or unwilling to comply with research requirements. Patients also completed the Physical Activity Readiness Questionnaire (PAR-Q) through a telephone interview. Patients with one or more potential exercise-related safety risks were excluded.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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72 participants in 2 patient groups

Physical activity group

Experimental group

Description:

Exercise intervention According to the guidelines of the American Sports Medicine Association (ACSM) and the National Fitness guidelines of the General Administration of Sport of China

Treatment:

Behavioral: Physical activity

control group

No Intervention group

Description:

Maintain the current state of physical activity, do not do physical activity intervention.