Effect of Physical Training Combined Cardiac Resynchronization Therapy in Heart Failure Patients

University of Sao Paulo General Hospital

Status: Completed

Conditions: Heart Failure

Treatments: Other: exercise training and/or CRT

Study type: Interventional

Funder types: Other

Identifiers

NCT01939795

PT & CRT

Details and patient eligibility

About

The investigators hypothesis that exercise training would potentiate the effects of cardiac resynchronization therapy in heart failure patients.

Enrollment: 40 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• QRS> 150 ms or 120-150ms associated dyssynchrony
• The etiology can be idiopathic, ischemic, hypertensive and Chagas' disease
• Ejection fraction <35%
• The optimal pharmacological treatment for heart failureExclusion Criteria:

Exclusion criteria

• Patients with pulmonary diseases, neurological diseases, renal, skeletal muscle diseases
• Patients with contraindications to implant a cardiac pacemaker
• Pregnancy
• New York Heart Association functional class IV
• Atrial fibrillation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 3 patient groups

Healthy People

No Intervention group

Description:

Control group

Untrained CRT

Experimental group

Description:

Untrained CRT patients

Treatment:

Other: exercise training and/or CRT

Exercise trained + CRT

Experimental group

Description:

Exercise-trained CRT patients

Treatment:

Other: exercise training and/or CRT