Effect of Physiological Ischemic Training on Patients With Atherosclerosis

Nanjing Medical University

Status: Enrolling

Conditions: Atherosclerosis

Treatments: Behavioral: exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT05091762

KY20210604-02

Details and patient eligibility

About

To study whether the resistance training with blood flow obstruction in patients in early atherosclerosis period can produce a beneficial effect on preventing atherosclerosis.

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. LDL > 3.11mmol/l and less than 5.63mmol/l;
2. No serious heart, blood vessel and other related diseases;
3. There were no skeletal and muscular diseases affecting sports training;
4. No regular exercise in the past half year (no more than 2 times a week, no more than 30 minutes each time);
5. Smoking less than 1 pack / year, no history of drinking.

Exclusion criteria

1. Haven't other serious heart and vascular diseases other than hyperlipidemia and / or bones and muscles that affect sports training Diseases;
2. Pregnant women and people with disabilities;
3. Other circumstances determined by the researcher not suitable for the study.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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200 participants in 8 patient groups

Blank control group

No Intervention group

Exercise group

Experimental group

Treatment:

Behavioral: exercise

Hyperlipidemia group

No Intervention group

Hyperlipidemia and medication group

No Intervention group

Hyperlipidemia and exercise group

Experimental group

Treatment:

Behavioral: exercise

Hyperlipidemia and medication and exercise group

Experimental group

Treatment:

Behavioral: exercise

Routine treatment group

No Intervention group

Routine treatment and exercise group

Experimental group

Treatment:

Behavioral: exercise