Effect of Plasma Rich in Growth Factors on Semen Quality

IVI Bilbao

Status: Completed

Conditions: Vascular Endothelial Growth Factor Overexpression

Treatments: Biological: PRGF in candidates for sperm donors

Study type: Observational

Funder types: Other

Identifiers

NCT02708537

1411-BIO-081-MF

Details and patient eligibility

About

The hypothesis is growing semen samples with plasma rich in growth factors (PRGF), because it could improve sperm motility in patients subsidiary TRA, ultimately improving pregnancy rates.

Full description

Platelet growth factors are a group of proteins involved in cellular communication modifying biological responses. Obtaining plasma rich in growth factors is already widespread and simple protocol technique that is being used in various areas of medicine with superb results. Described many of the growth factors present in the PRGF are related to sperm parameters, especially motility The described effects have been studied in mammalian and each growth factor individually. PRGF contains a pool of growth factors and therefore be interesting to analyze their effect on various sperm parameters.

One of those parameters is very important for fertilization sperm motility, since the lack of it will prevent displacement by the cervix to meet the egg in the fallopian tube.

Enrollment: 20 patients

Sex: Male

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18-35 years
• more than 5 million sperm per milliliter

Exclusion criteria

• Not having genetic and infectious diseases
• Do not suffer mental illness
• Have a family study determined that there is no risk of hereditary diseases
• There have fathered more than 6 children in the country

Trial design

20 participants in 1 patient group

PRGF in candidates for sperm donors

Description:

Prospective study of 58 candidates for sperm donors clinic IVI Bilbao.

Treatment:

Biological: PRGF in candidates for sperm donors