Effect of Platelet Rich Plasma on Outcome of Narrow Band UVB in Treatment of Vitiligo; Clinical and Histopathological Study

Sohag University

Status

Active, not recruiting

Conditions

Management of Stable Vitiligo

Treatments

Procedure: platelet rich plasma, narrow band UVB

Study type

Interventional

Funder types

Other

Identifiers

NCT06370650

soh-med-24-1-9

Details and patient eligibility

About

For each patient, one side of body will be treated with NB-UVB alone while the other side will be treated with NB-UVB therapy in addition to intradermal injection of PRP every 2 weeks. Patients will be photographed at the first visit, in the middle and at the end of therapy. Each patient will sign a written consent form to be included in the study and to be photographed.

Enrollment

30 patients

Sex

All

Ages

15 to 50 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients with stable non segmental vitiligo. (Absence of koebnerization, absence of new lesion and absence of widening of the existing lesions).

Patients have more than 15 years.

Exclusion criteria

Patients have active vitiligo (appearance of new lesion, history of koebnerization).

Pregnant and lactating women. History of keloid formation. Anemia (hemoglobin level <10gm/dl), thrombocytopenia (platelet count <100,000 /µL), coagulopathies or patients on anticoagulant therapy and patients with iron deficiency.

Patients taking drugs that prolong bleeding time such as Aspirin and vitamin E Patients taking treatment of vitiligo in last 2 months