Effect of Pneumoperitoneum on Cognitive Function and Regional Cerebral Oxygen Saturation (rSO2pneumo)

Gachon University Gil Medical Center

Status: Completed

Conditions: Pneumoperitoneum

Study type: Observational

Funder types: Other

Identifiers

NCT01826955

GIRBA2712-2012

Details and patient eligibility

About

The investigators hypothesized that the pneumoperitoneum with reverse Trendelenburg position could alter the rSO2 and early postoperative cognitive function.

Full description

Laparoscopic gastrectomy requires a reverse-Trendelenburg position and prolonged pneumoperitoneum and it could cause significant changes in cerebral homeostasis and lead to cognitive dysfunction. We compared changes in haemodynamic variables, regional cerebral oxygen saturation, and early postoperative cognitive function in patients undergoing laparoscopic gastrectomy in the reverse Trendelenburg position with those patients that underwent conventional open gastrectomy.

Enrollment: 60 patients

Sex: All

Ages: 20 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA class I or II, aged 20 to 70 yrs

Exclusion criteria

• Patients with morbid obesity (body mass index > 30 kg/m2) or a history of cerebrovascular or respiratory disease were excluded.

Trial design

60 participants in 2 patient groups

Open gastrectomy

Description:

patient who undergoing open gastrectomy

laparoscopic gastrectomy

Description:

patient who undergoing laparoscopic gastrectomy