Effect of Pneumoperitoneum on Remifentanil Requirements in the Surgical Pleth Index-guided Analgesia

Ajou University School of Medicine

Status: Completed

Conditions: Gastric Cancer

Treatments: Other: High end-tidal CO2; Other: Low CO2 group

Study type: Interventional

Funder types: Other

Identifiers

NCT03788447

AJIRB-MED-THE-18-410

Details and patient eligibility

About

The primary purpose of this study is to investigate the effect of pneumoperitoneum on remifentanil requirements in the surgical pleth index-guided analgesia for laparoscopic gastrectomy.

Enrollment: 74 patients

Sex: All

Ages: 19 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• laparoscopic gastrectomy under general anesthesia

Exclusion criteria

• atypical hemoglobin disease, infective state, cardiovascular disease, peripheral vascular disease

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

---

74 participants in 2 patient groups, including a placebo group

High CO2 group

Experimental group

Description:

end tidal CO2 : 40-45 mmHg

Treatment:

Other: High end-tidal CO2

Low CO2 group

Placebo Comparator group

Description:

end tidal CO2 : 30-35 mmHg

Treatment:

Other: Low CO2 group