Effect of Position During Spinal Anesthesia on Hemodynamic Change in Cesarean Section

Prince of Songkla University

Status: Completed

Conditions: Hypotension

Treatments: Procedure: Right; Procedure: Left

Study type: Interventional

Funder types: Other

Identifiers

NCT02253381

REC: 57-195-08-1

Details and patient eligibility

About

Hypotension is the most common complications after spinal anesthesia especially in pregnant patients who undergoing cesarean section. Position during spinal anesthesia may be altering the hemodynamic. For right lateral decubitus, the enlarged uterus compresses inferior vena cava that may decrease venous return and cardiac output. This leads to hypotension.The hypothesis is the right lateral position during spinal anesthesia in pregnant women will be had hemodynamic changing more than the left lateral position. This objective is to compare hemodynamic change between left and right lateral position during spinal anesthesia in pregnant women undergoing cesarean section.

Full description

Study design: A randomized controlled trial

Study setting:

The study will be conducted in the operating rooms at Songklanagarind Hospital, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand

Study period:

The total duration of participation in the randomized study is up to the operative day.

Study population:

Pregnant patients undergoing cesarean section receiving spinal anesthesia with 0.5% bupivacaine and 0.2 mg morphine total volume 2.2 ml.

Study sample:

Inclusion criteria

1. Signed informed consent
2. Pregnancy
3. Spinal anesthesia with 0.5% bupivacaine and 0.2 mg morphine total volume 2.2 ml
4. Elective and emergency surgery

Exclusion criteria

1. Contraindication for spinal anesthesia
2. Complicated pregnancy such as maternal heart disease, eclampsia, severe fetal distress, abruption placenta, twin pregnancy, and placenta previa totalis
3. Maternal height < 150 cm.

Enrollment: 140 patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

• Signed informed consent
• Term pregnancy
• Spinal anesthesia with 0.5% bupivacaine and 0.2 mg morphine total volume 2.2 ml

Exclusion criteria

• Contraindication for spinal anesthesia
• Height < 150 cm.
• Complicated pregnancy e.g. heart disease, preclampsia, eclampsia, diabetes millitus, twin, abrupt placenta, placenta pre via, and fetal distress
• Failed spinal anesthesia

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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140 participants in 2 patient groups

Right lateral decubitus position

Active Comparator group

Description:

Right lateral decubitus position during spinal anesthesia

Treatment:

Procedure: Right

Left lateral decubitus position

Active Comparator group

Description:

Left lateral decubitus position during spinal anesthesia

Treatment:

Procedure: Left