Effect of Post-operative Chlorhexidine on Postoperative Pain and Complications After Surgical Removal of Mandibular Third Molars (RITOR)

Isala

Status: Completed

Conditions: Third Molars Extraction

Treatments: Other: Chlorhexidine Digluconate Mouthwash without Alcohol

Study type: Interventional

Funder types: Other

Identifiers

NCT06880952

71727.075.20

Details and patient eligibility

About

This study aimed to assess the impact of postoperative chlorhexidine use on pain management following mandibular third molar removal

In this prospective, randomized controlled trial,130 patients who underwent mandibular third molar surgical removal were divided into two groups: one group used chlorhexidine for postoperative rinsing and the other did not rinse. Pain levels, measured using the Numeric Rating Scale (NRS), were recorded daily for the first seven days post-surgery. Paired-samples t-tests were utilized for data analysis.

Enrollment: 145 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy adults (18+) referred by their dentist for third molar removal

Exclusion criteria

• active pericoronitis or other infections
• planned coronectomy
• trismus
• chronic pain
• pregnancy
• known allergies to local anesthesia

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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145 participants in 2 patient groups

Post-operative rinsing with chlorhexidine

Other group

Description:

In the rinsing group, the patients received a bottle of 0,2% chlorhexidine

Treatment:

Other: Chlorhexidine Digluconate Mouthwash without Alcohol

No post-operative rinsing

No Intervention group

Description:

Those allocated to the control group received no post-operative rinsing