Effect of Pranayama on Periodontal Health

Meenakshi Ammal Dental College and Hospital

Status and phase: Completed; Early Phase 1

Conditions: Chronic Periodontitis

Treatments: Behavioral: Pranayama; Procedure: Scaling and root planing

Study type: Interventional

Funder types: Other

Identifiers

NCT02967861

MAHER-MU-002-IEC/2016

Details and patient eligibility

About

The objective of the study was to evaluate the levels of Peroxisome proliferator-activated receptor gamma (PPAR-γ), Nuclear factor-kappa B (NF-kB) and the presence of red complex microorganisms (RCM) such as Treponema denticola (T.d), Porphyromonas gingivalis (P.g) and Tannerella forsythia (T.f) in the subgingival tissues of chronic periodontitis subjects before and after intervention with pranayama as an adjunct to scaling and root planing.

Full description

Sixty chronic periodontitis subjects were selected out of which 30 subjects (control group) were treated with scaling and root planing (SRP) and 30 subjects (pranayama group) also underwent SRP and pranayama for 3 months. Clinical parameters were recorded and the presence of PPAR-γ, NF-kB and RCM were assessed at baseline and after 3 months

Enrollment: 60 patients

Sex: All

Ages: 30 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• presence of at least 20 teeth
• Probing pocket depth ≥ 5 mm

Exclusion criteria

• aggressive periodontitis
• systemic disorders
• pregnant & lactating females
• smokers & alcoholics
• immunocompromised individuals

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 2 patient groups, including a placebo group

SRP & pranayama (lifestyle modification)

Active Comparator group

Description:

30 chronic periodontitis subjects treated with SRP \& pranayama for 3 months

Treatment:

Behavioral: Pranayama

Scaling and root planing

Placebo Comparator group

Description:

30 chronic periodontitis subjects treated with scaling and root planing only

Treatment:

Procedure: Scaling and root planing