Effect of Pre-Warming of Local Anesthesia in Reducing Pain Perception During Injection in Children

Andrew Emad

Status: Completed

Conditions: Dental Anesthesia; Local Anesthesia

Treatments: Other: Maxillary infiltration technique; Other: Local anesthesia solution at room temperature; Other: Inferior alveolar nerve block technique; Other: Local anesthesia solution pre-warmed to 40°C; Other: Local anesthesia solution pre-warmed to 37°C

Study type: Interventional

Funder types: Other

Identifiers

NCT06519838

1/2023

Details and patient eligibility

About

The aim of the current study was to evaluate the pain perception upon injection of pre-warmed dental anesthetic solution (at 370C and 400C) versus that at room temperature (Average 23 degrees) during Maxillary Infiltration and Mandibular Inferior Alveolar Nerve Block techniques in children

Enrollment: 72 patients

Sex: All

Ages: 5 to 7 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Healthy patients with ASA 1 or 2 Classification.
• Patients with Frankl Behavior Classification 3-4.
• Patients having at least one carious primary molar that requires dental treatment under the effect of local anesthesia.
• Parents' willingness to participate through informed written consent.

Exclusion criteria

• Patients with previous negative dental experience.
• Patients complaining of cellulitis or infection spreading in the fascial spaces.
• Patients who have received analgesics within the previous 12 hours before receiving the required dental treatment.
• Patients with any Intellectual Impairment.
• Patients with a history of allergy from any of the components of the dental anesthetic carpule.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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72 participants in 6 patient groups

Maxillary infiltration at room temperature

Active Comparator group

Treatment:

Other: Local anesthesia solution at room temperature

Other: Maxillary infiltration technique

Inferior alveolar nerve block at room temperature

Active Comparator group

Treatment:

Other: Inferior alveolar nerve block technique

Other: Local anesthesia solution at room temperature

Maxillary infiltration pre-warmed to 37°C

Experimental group

Treatment:

Other: Local anesthesia solution pre-warmed to 37°C

Other: Maxillary infiltration technique

Inferior alveolar nerve block pre-warmed to 37°C

Experimental group

Treatment:

Other: Local anesthesia solution pre-warmed to 37°C

Other: Inferior alveolar nerve block technique

Maxillary infiltration pre-warmed to 40°C

Experimental group

Treatment:

Other: Local anesthesia solution pre-warmed to 40°C

Other: Maxillary infiltration technique

Inferior alveolar nerve block pre-warmed to 40°C

Experimental group

Treatment:

Other: Local anesthesia solution pre-warmed to 40°C

Other: Inferior alveolar nerve block technique