Effect of Precise Grip Strength Training on PICC Catheter-Related Thrombosis in Cancer Patients

Junyan Zhao

Status: Completed

Conditions: Breast Cancer; Colon Cancer; Lung Cancer; Liver Cancer; Stomach Cancer; Rectal Cancer

Treatments: Behavioral: Precision grip training; Behavioral: Health education on routine grip strength training; Behavioral: Use maximum strength grip training

Study type: Interventional

Funder types: Other

Identifiers

NCT05638048

YXLL-KY-2022(057)

Details and patient eligibility

About

In this study, color Doppler ultrasound diagnostic instrument and electronic grip device were used to determine the best grip strength of patients with tumor PICC catheterization, formulate precise and standardized grip strength training guidance for them, provide personalized functional exercise health education, and observe the impact of precise grip strength training guidance on Peripheral central venous catheter-associated thrombosis. To provide a reference for clinical prevention of Peripheral central venous catheter-associated thrombosis in the future.

Enrollment: 270 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Cancer patients undergoing chemotherapy throughout their treatment in our hospital
• Patients with PICC implanted for the first time and maintained at our hospital;
• Age 18-60 years;
• Normal cognitive function;
• the clenching movement is barrier-free;
• The material and performance of PICC catheter are silicone three-way valve catheter;
• Catheter placement under the guidance of portable color Doppler ultrasound diagnostic instrument;
• Voluntarily participate and sign the informed consent form.

Exclusion criteria

• Patients treated with combined radiotherapy;
• Patients with coagulation dysfunction;
• Patients who need to use anticoagulant drugs due to underlying diseases;
• Puncture times more than 1 time;
• The blood flow velocity of catheterization vessel in calm state was less than 4.78cm/s.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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270 participants in 3 patient groups

The control group

Active Comparator group

Description:

Patients were routinely implanted with PICC and received routine health education. The content of health education included face-to-face language explanation of the whole process of catheter knowledge, issuing catheter maintenance manual, issuing ordinary grip ball and telling how to use it, and follow-up.

Treatment:

Behavioral: Health education on routine grip strength training

Experiment 1 set

Experimental group

Description:

Patients were routinely implanted with PICC, and the optimal duration-relaxation time of grip strength training was adopted on the basis of health education in the control group.

Treatment:

Behavioral: Use maximum strength grip training

Experiment 2 set

Experimental group

Description:

On the basis of control group 1. Determine the best grip strength On the basis of the control group, color Doppler ultrasound and electronic grip force were used to record the optimal grip strength of patients to achieve effective blood flow velocity before and 24 hours after PICC insertion. 2. Design precise grip strength training guidance program On the basis of the control group, the patients were instructed to perform grip strength training according to the determined best grip strength and the best duration of clenching and relaxation time.

Treatment:

Behavioral: Precision grip training