Effect of Pregabalin on the Postoperative Analgesia in RFA of Focal Lesions in the Liver (pregabalin)

Sherief Abd-Elsalam

Status and phase: Unknown; Phase 4

Conditions: Hepatocellular Cancer

Treatments: Other: Placebo; Drug: Pregabalin 150mg

Study type: Interventional

Funder types: Other

Identifiers

NCT03151213

amr magdy

Details and patient eligibility

About

The study aimed to investigate the preemptive analgesia efficacy of of preemptive pregabalin for the postoperative pain management after radiofrequency ablation (RFA) of liver cancer.

Full description

Our data will investigate if preemptive administration of pregabalin will have a role in reducing postoperative pain after radiofrequency ablation (RFA) of liver cancer.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• HCC patients, Child A, B, scheduled for Radiofrequency ablation of HCC.

Exclusion criteria

• Encephalopathy, Renal impairment

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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100 participants in 2 patient groups, including a placebo group

Pregabalin

Active Comparator group

Description:

Pregabalin 150 mg before intervention

Treatment:

Drug: Pregabalin 150mg

Placebo

Placebo Comparator group

Description:

Placebo before intervention

Treatment:

Other: Placebo