Effect of Processed Blueberry on Blood Glucose and Antioxidant Status in Human Adults

Mount Saint Vincent University

Status: Completed

Conditions: Blood Glucose

Treatments: Other: Food-2; Other: Food-1

Study type: Interventional

Funder types: Other

Identifiers

NCT04396262

2019-204

2015-102

Details and patient eligibility

About

Canada's Food Guide (2007) recommended 7-10 servings of fruits and vegetables per day for a normal adult population. Although fruit juice (125 ml) is considered as one serving of fruits, the consumption of some fruit juices may be limited due to their high amount of sugar. The consumption of sugary drinks can lead to a rapid rise in postprandial glycaemia. Wild blueberries, due to their high level of anthocyanins, may provide multiple health benefits including improved blood glucose control, however, the consumption of fresh berries is limited by their short seasonal availability. Hydro-Thermodynamic (HTD) processing of blueberries allows the processing of whole berries including their skin and seeds into a beverage with the amount of anthocyanins comparable with fresh berries. The objective of the study is to investigate the effect of HTD-processed blueberries on postprandial glycaemia and antioxidant activity.

Enrollment: 25 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy adults
• Body mass index (BMI) within normal range (18.5-24.9 kg/m2 for adults)

Exclusion criteria

• Chronic metabolic diseases or inflammatory conditions
• Smokers
• A medication that influences glucose control or gastrointestinal function
• Known allergies
• Intellectual disabilities

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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25 participants in 2 patient groups

HTD-blueberry beverage with white bread

Experimental group

Description:

The beverage prepared using hydro-thermodynamic processing of whole wild blueberries.

Treatment:

Other: Food-1

Sweetened water (control) with white bread

Experimental group

Description:

The water control of the same volume and with the same amount of available carbohydrate as HTD-blueberry beverage.

Treatment:

Other: Food-2