Effect of Protein Blend Supplementation During Exercise Training on Muscle Growth and Strength

DuPont

Status: Completed

Conditions: Muscle

Treatments: Dietary Supplement: Placebo; Dietary Supplement: Blend; Dietary Supplement: Whey

Study type: Interventional

Funder types: Industry

Identifiers

NCT01749189

CRC-D-179

Details and patient eligibility

About

This study will investigate the effects of a soy/dairy protein blend on muscle growth and strength. In sports nutrition and in aging it is important to have healthy muscles. This can be achieved with exercise and nutrition. Consumption of protein following resistance exercise can promote healthy muscle growth and help improve strength. Young healthy men will be studied during a 12 week resistance exercise training program and be given protein supplements every day during the study. The hypothesis is that a blend of soy, whey and casein will induce a greater muscle gain and strength increase than the control.

Enrollment: 58 patients

Sex: Male

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Stable body weight, healthy, males aged 18-35

Exclusion criteria

1. Exercise training (>2 weekly sessions of moderate to high intensity aerobic or resistance exercise)
2. Resistance Training (>2 weekly sessions of moderate to high intensity) within the past six months
3. Any orthopedic injury that prohibits participation in the exercise training
4. Significant heart, liver, kidney, blood, or respiratory disease
5. Peripheral vascular disease
6. Diabetes mellitus or other untreated endocrine disease
7. Active cancer (all groups) and history of cancer
8. Acute infectious disease or history of chronic infections (e.g. TB, hepatitis, HIV, herpes)
9. Recent (within 6 months) treatment with anabolic steroids, or corticosteroids.
10. Alcohol or drug abuse
11. Tobacco use (smoking or chewing)
12. BMI range will be (20-29.9 kg/m2) to exclude for Malnutrition (hypoalbuminemia, and/or hypotransferrinemia) and Obesity
13. Low hemoglobin levels (below normal values)
14. Food allergies (including milk and soy)
15. Individuals on a Vegetarian Diet
16. Females
17. Average protein intake < 0.6 or >1.8 g/kg per day
18. Taking dietary supplements such as green tea, creatine, ribose, whey or soy protein, etc. within the past 6 months
19. Currently on a high-soy diet or high dairy diet (consuming >2 servings of soy per day or >6 servings of dairy)

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

---

58 participants in 3 patient groups, including a placebo group

Placebo

Placebo Comparator group

Description:

Placebo dry blended beverage (carbohydrate)

Treatment:

Dietary Supplement: Placebo

Blend

Experimental group

Description:

A dry blended beverage containing a protein blend of soy, whey and casein

Treatment:

Dietary Supplement: Blend

Whey

Active Comparator group

Description:

A dry blended beverage containing Whey protein

Treatment:

Dietary Supplement: Whey