Effect of Protein Consumption and Resistance Training on Body Composition, Muscular Strength and Functional Capacity in the Elderly

Federal University of Health Science of Porto Alegre

Status: Completed

Conditions: Elderly; Sarcopenia

Treatments: Other: Exercise training + placebo (maltodextrin); Dietary Supplement: Exercise training + whey protein

Study type: Interventional

Funder types: Other

Identifiers

NCT03862937

FUHSPortoAlegre2019

Details and patient eligibility

About

The increase in life expectancy of the world population is associated with a higher incidence of diseases, leading to functional incapacity and dependence in old age. Aging is usually accompanied by progressive loss of muscle mass, muscular strength and functional capacity, possibly exacerbated by inactivity and low protein and energy consumption of elderly individuals. However, the response to strength training, as well as the daily recommendation of protein and other factors related to sarcopenia in this population seem not to be well understood. Objective: To evaluate the effect of protein intake and resistance training on body composition, muscle strength and functional capacity in the elderly. METHODS: A randomized placebo-controlled clinical trial will be conducted with 38 elderly people, ≥ 60 years old, sedentary, and body mass index between 22 and 30 kg / m2. All those who agree to participate will be randomized into two groups (intervention or placebo) and will undergo an initial assessment consisting of food consumption analysis through the application of the three-day food record, assessment of muscle thickness of the thigh and arm by muscle ultrasonography, evaluation of body composition by dual energy X-ray absorptiometry (DEXA), dynamic maximal strength (1RM) test of knee extension and elbow flexion, peak torque test of knee extension, functional capacity tests and quality of life questionnaire (SF-36). The elderly will participate in resistance training for 12 weeks, two session per week. The intervention group will be supplemented with whey protein isolate (2x / day - 20g for breakfast and 20g for dinner) and the placebo group will receive maltodextrin (2x / day - 20g for breakfast and 20g for dinner). All outcomes will be assessed before and after the 12-week resistance training period.

Enrollment: 38 patients

Sex: All

Ages: 60 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Be 60 or older, and in the case of women, they must be postmenopausal (interruption of menstruation for more than one year).
• Have not participated in any systematic exercise program for at least six months prior to the start of this project.
• To have a body mass index (BMI) between 22 and 30 kg / m2.
• Are not cardiopathic, diabetic or have any other metabolic disease.
• Do not present joint problems or any other injury that prevents the proper execution of the exercises of the training routine.
• Non-smoker or have quit smoking for at least five years ago.
• Release of the doctor (medical certificate) to perform the physical exercises.

Exclusion criteria

• Do not participate in at least 20 training sessions or miss more than three consecutive training sessions.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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38 participants in 2 patient groups, including a placebo group

Experimental

Experimental group

Description:

The experimental group will perform 12 weeks of strength training twice a week associated with whey protein supplementation.

Treatment:

Dietary Supplement: Exercise training + whey protein

Placebo

Placebo Comparator group

Description:

The placebo group will perform 12 weeks of strength training twice a week associated with maltodextrin supplementation.

Treatment:

Other: Exercise training + placebo (maltodextrin)