Effect of PRP With Physiotherapy on Shoulder Impingement

Istinye University

Status: Completed

Conditions: Functionality; Shoulder Impingement Syndrome; Platelet-Rich Plasma

Treatments: Other: Conventional physiotherapy programme; Drug: Platelet Rich Plasma (PRP); Other: IPRP-PT Study Protocol

Study type: Interventional

Funder types: Other

Identifiers

NCT07410208

Decision number 12

Details and patient eligibility

About

Background Shoulder impingement syndrome is the most common disorder of the shoulder. Study results on the effectiveness of treatment options are inconclusive and limited. Therefore, more evidence is needed for long-term results Objective To investigate the effectiveness of the ideal physiotherapy protocol (IPRP-PT) applied after platelet-rich plasma (PRP) injection on pain and functionality in patients with shoulder impingement syndrome, and to propose an alternative treatment protocol.

Methods The study was performed in 54 patients with shoulder impingement syndrome who were injected with PRP. Patients were randomly divided into two equal groups. For 21 days, the study group received IPRP-PT study protocol, conventional physiotherapy and home exercise programme, while the control group received only conventional physiotherapy programme. Normal range of motion, muscle strength and posture were assessed. In addition, short form Mc-gill (SF-MPQ), Visual Analogue Scale (VAS), Constant Murley Shoulder Score, Disabilities of the Arm, Shoulder and Hand Questionnaire (DASH), Functional Impairment Test-Hand and Neck/Shoulder/Arm (FIT-HaNSA), were used.

Enrollment: 54 patients

Sex: All

Ages: 30 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria

• Age between 30-65 years
• Diagnosis of stage I or II shoulder impingement syndrome
• Received one dose of PRP injection
• Referred for and seeking physical therapy
• Voluntary participation
• Ability to cooperate with the study procedures

Exclusion Criteria

• Previous surgical treatment for shoulder impingement syndrome
• Presence of other orthopedic conditions (e.g., shoulder fractures)
• Presence of neuromuscular disease
• Presence of a pacemaker
• Pregnancy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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54 participants in 2 patient groups

Study group

Experimental group

Treatment:

Other: IPRP-PT Study Protocol

Other: Conventional physiotherapy programme

Drug: Platelet Rich Plasma (PRP)

Control Group

Active Comparator group

Treatment:

Other: Conventional physiotherapy programme

Drug: Platelet Rich Plasma (PRP)