Effect of Pulse Fractions on Indices on Cardiovascular Disease and Diabetes Risk Factors

University of Manitoba

Status and phase: Completed; Phase 2

Conditions: Cardiovascular Disease

Treatments: Other: White wheat flour; Other: Fractionated pea flour; Other: Whole yellow pea flour

Study type: Interventional

Funder types: Other

Identifiers

NCT00839774

B2006:129

Details and patient eligibility

About

The purpose of this study is to determine if whole and fractionated yellow pea flour, administered at USDA recommended dosages (50 g/day), improve risk factors associated with cardiovascular disease and diabetes.

Enrollment: 23 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• BMI between 25 and 40 kg/m2
• Hypercholesterolemic

Exclusion criteria

• Smoking
• Use of prescription and natural lipid lowering therapies
• Myocardial infarction
• Coronary artery bypass
• Angina
• Congestive heart failure,
• Inflammatory bowel disease
• Pancreatitis
• Renal disease
• Diabetes
• Chronic alcohol usage (> 2 drinks/day).
• Cancer
• Eating disorders
• Expending > 4000 kcal/week through exercise

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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23 participants in 3 patient groups

1

Experimental group

Description:

Whole yellow pea flour

Treatment:

Other: Whole yellow pea flour

2

Experimental group

Description:

Fractionated yellow pea flour

Treatment:

Other: Fractionated pea flour

3

Experimental group

Description:

White wheat flour

Treatment:

Other: White wheat flour