Effect of Pumpkin Seeds on the Dietary Fatty Acid Intake and Blood Pressure in Women (PSS1)

Texas Woman's University

Status: Withdrawn

Conditions: Blood Pressure; Cardiovascular Disease

Treatments: Other: Pumpkin Seeds

Study type: Interventional

Funder types: Other

Identifiers

NCT01928966

TWU-1PS

Details and patient eligibility

About

The purpose of this study is to determine if the inclusion of 1.5 ounces of pumpkin seeds per day in the diet of women will alter dietary fatty acid intake or blood pressure.

Full description

Cardiovascular disease is the number one cause of morbidity and mortality in United States. Diets high in polyunsaturated and monounsaturated fatty acids have been shown to decrease the risk of cardiovascular disease. Pumpkin seeds are a good source of monounsaturated and polyunsaturated fatty acids. Oil extracted from pumpkin seeds has been shown to lower blood pressure. One purpose of this study is to determine whether eating 1.5 ounces of pumpkin seeds per day will improve polyunsaturated and monounsaturated fatty acid intake in the diet in healthy adult women. Another purpose of this study is to determine whether eating 1.5 ounces of pumpkin seeds a day will lower blood pressure.

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Female
• Over the age of 18
• Able to read, write, and speak English
• Able to keep a three-day diet diary
• Willing and able to consume pumpkin seeds

Exclusion criteria

• Pregnant or planning to become pregnant
• Allergic to pumpkin seeds
• High blood pressure
• Regularly consuming pumpkin seeds (more than 4 times per month)
• Taking blood pressure medication
• Liver disease
• Kidney disease
• Gastrointestinal disease
• History of bariatric surgery
• History of a major cardiovascular event
• Heart disease
• Currently undergoing cancer treatment (except nonmelanoma cancer)
• Following a weight control diet
• Following a disease specific diet
• Following a vegan diet
• Have a diagnosed eating disorder

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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0 participants in 2 patient groups

Group I - Pumpkin Seeds

Active Comparator group

Description:

First four weeks of study: consume perceived normal diet; Second four weeks of study: receive 1.5 ounces of pumpkin seeds per day for consumption; Third four weeks of the study: consume their perceived normal diet.

Treatment:

Other: Pumpkin Seeds

Group II - Pumpkin Seeds

Active Comparator group

Description:

First four weeks of study: consume perceived normal diet; Second four week period: consume perceived normal diet; Third four week period: receive 1.5 ounces of pumpkin seeds per day for consumption.

Treatment:

Other: Pumpkin Seeds