Effect of Pupilometer Guided Analgesia on Postoperative Pain (PUPIL_pain)

Daegu Catholic University Medical Center

Status

Completed

Conditions

Reflex, Pupillary

Anesthesia, General

Cholecystectomy, Laparoscopic

Treatments

Procedure: Pupilometer guided anesthesia

Procedure: SPI guided anesthesia

Study type

Interventional

Funder types

Other

Identifiers

NCT03794271

DCMC#6

Details and patient eligibility

About

In this study, the investigators measure a pupil size every 5 minutes during the operation in patients undergoing laparoscopic cholecystectomy under general anesthesia. The investigators would compare the postoperative pain intensity between the group adjusted the anesthetic drug concentration based on the changes of the pupil (Pupil group) and the group based on the changes of a surgical pleth index (SPI group).

Enrollment

84 patients

Sex

All

Ages

20 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients aged 20 to 65 yr, American Society of Anesthesiologist Physical status(ASA PS) I to II, scheduled for a laparoscopic cholecystectomy under general anesthesia

Exclusion criteria

Presence of ophthalmologic diseases such as Horner's syndrome or Sjogren's disease.
Presence of neurologic or metabolic diseases
Medicated that could interfere with the autonomous nervous system (e.g., b- blockers, anticholinergics)
History of substance abuse or psychiatric disease with chronic pain or preoperative analgesics with pacemaker or arrhythmia