Effect of PVE on Surgical Outcomes and Long-term Survival in Perihilar Cholangiocarcinoma

Seoul National University

Status: Completed

Conditions: Biliary Tract Cancer; Portal Vein Embolization

Treatments: Procedure: Potal vein embilization

Study type: Observational

Funder types: Other

Identifiers

NCT06222619

H-2001-092-1095

Details and patient eligibility

About

Portal vein embolization is often recommended to reduce the risk of postoperative liver failure and mortality. In this retrospective cohort study, researchers investigated the effect of portal vein embolization in patients with resectable perihilar cholangiocarcinoma bismuth type III and IV.

Enrollment: 136 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

1. patients with Bismuth type III or IV stricture on radiological examination, including computed tomography (CT) or magnetic resonance cholangiography
2. patients with perihilar cholangiocarcinoma histologically confirmed by surgical resection or forceps biopsy/brush cytology under endoscopic retrograde cholangiopancreatography or through the percutaneous transhepatic biliary drainage tract.

Exclusion criteria

1. patients with unresectable perihilar cholangiocarcinoma
2. patients who refused treatment
3. patients with other concomitant malignancies.

Trial design

136 participants in 3 patient groups

Resection without PVE

Description:

Resection of bile duct and associated hemi-liver without portal vein embilzation

Resection after PVE

Description:

Resection of bile duct and associated hemi-liver after portal vein embilzation

Treatment:

Procedure: Potal vein embilization

No resection after PVE

Description:

No resection of bile duct and associated hemi-liver after portal vein embilzation

Treatment:

Procedure: Potal vein embilization