Effect of Radiation Therapy Among Head and Neck Cancer Patients on the Inner Ear Function

Tel Aviv Sourasky Medical Center

Status: Unknown

Conditions: Head and Neck Cancer Patients Treated With Radiotherapy

Treatments: Diagnostic Test: Audiometry and tympanometry, vHIT, VEMP, ENG

Study type: Observational

Funder types: Other

Identifiers

NCT04214769

403-19

Details and patient eligibility

About

Aims: 1. To evaluate the effects of radiation therapy on the inner ear, among patients treated with radiation therapy for head and neck cancers using a wide battery of tests (Audiometry and tympanometry, vHIT, VEMP, ENG) ; 2. To correlate the mean total radiation dose to the cochlea with the effects on audiological and vestibular function

Enrollment: 17 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Females and males, Age: ≥ 18 years old
• Patients diagnosed Head and Neck cancers, not treated previously
• Planned for radiation therapy in which the inner ear will be radiated

Exclusion criteria

• Patients who were previously diagnosed with a vestibular disorder
• Previous middle or inner ear anomaly
• Failure to complete the whole course of radiation therapy
• More than one course of radiation therapy
• Patients treated with concurrent ototoxic chemotherapy
• Pregnant women
• Patients who will not sign an informed consent form
• Helpless or incompetent patients

Trial design

17 participants in 1 patient group

Head and Neck Cancer patients

Treatment:

Diagnostic Test: Audiometry and tympanometry, vHIT, VEMP, ENG