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Effect of Radical Prostatectomy on Involuntary Pelvic Floor Muscle Contraction

P

Pierre and Marie Curie University

Status

Completed

Conditions

Lower Urinary Tract Symptoms

Study type

Observational

Funder types

Other

Identifiers

NCT03574298
P GREEN 0001

Details and patient eligibility

About

This study evaluate the effect of radical prostatectomy on involuntary pelvic floor muscle contraction

Full description

Radical prostatectomy may cause stress urinary incontinence (SUI). That poses problem in terms of quality of life. There are many treatment options available for patients with SUI, but the exact mechanism is not known. We compared, in continent and incontinent men post-radical prostatectomy, the correlation between the temporal course of pelvic floor activation during cough.

Simultaneously, recordings of electromyographic activity of external anal sphincter (EAS EMG) and external intercostal muscle (EIC EMG) during coughing will be made with a pair of pre-gelled electrodes. Cough effort cause an involuntary pelvic contraction. Intercostals muscles recording was chosen because they are one of the muscular components of cough initiation with diaphragm muscle. 24h pad-weighing test is used to quantify urinary incontinence. We will measure the latency between the onset of the EIC EMG and the EAS EMG (RT3), during a cough effort. We will also measure the duration of the contraction, the maximum EAS EMG activity and the area under the curve.

Enrollment

22 patients

Sex

Male

Ages

18 to 100 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Follow in neuro-urology for lower urinary tract symptoms
  • Radical Prostatectomy

Exclusion criteria

  • Perineal Radiotherapy
  • Surgery for stress urinary incontinence

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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