Effect of Ramadan Fasting on Muslim Recipients After Living Donor Liver Transplantation

Ain Shams University

Status: Completed

Conditions: Liver Transplantation

Treatments: Behavioral: Fasting Ramadan

Study type: Observational

Funder types: Other

Identifiers

NCT03592524

Ramadan fasting and liver

Details and patient eligibility

About

The study aimed to assess the possibility of Ramadan fasting and to start protocol of adapting immunosupression regiment and scheduled follow up for patients wishing to fast after liver transplantation (LT).

Full description

Very limited data in the literature about how to apply Ramadan fasting in the post liver transplant setting. The timing of Ramadan is changeable according to the lunar year and according to time of down and sunset in each country. In Egypt, for example, Ramadan fasting this year started 17th of May and finished 14th June with average fasting hours of 15-16 hours The study aimed to assess the possibility of Ramadan fasting and to start protocol of adapting immunosupression regiment and scheduled follow up for patients wishing to fast after LT.This prospective study included 45 recipients who underwent LT at Ain Shams Center for Organ Transplant (ASCOT), Cairo, Egypt.

Enrollment: 45 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• • Recipients completed their first year after LDLT

  • Normal liver and renal functions at least in the last 3 months before fasting
  • No reported rejection episodes in the last 6 months before the study
  • Recipients wishing to fast Ramadan
  • Informed consent about the study

Exclusion criteria

• • First year of LDLT

  • Recipients transplanted for Budd Chiari syndrome
  • Recipients with vascular stents (hepatic artery , portal vein or hepatic vein stents) requiring long life anticoagulation
  • Creatinine clearance <60 ml/min or serum creatinine >1.5 mg/dl at time of initial enrolment in the study.