Effect of Recombinant Human Bone Morphogenetic Protein-2 With an Absorbable Collagen Sponge on Stability of Dental Implant: (Split Mouth Randomized Clinical Trial Study. (rhBMP-2)

University of Baghdad

Status and phase

Enrolling

Phase 1

Conditions

Hypertension

Blood Disease

Diabetes Mellitus

Treatments

Biological: rhBMP-2

Study type

Interventional

Funder types

Other

Identifiers

NCT05719181

528622

Details and patient eligibility

About

Effect of Recombinant Human Bone Morphogenetic Protein-2 with an Absorbable Collagen Sponge on Stability of Dental Implant: (Split Mouth Randomized Clinical Trial Study.

Full description

The Primary outcome will be measuring the effect of rhBMP- 2/ACS in improving the secondary stability of dental implant by using RFA in comparison to control group.

Secondary outcome association of the effect of other factors (ridge dimension, bone density) on dental implant stability.

Enrollment

32 estimated patients

Sex

All

Ages

25 to 70 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Patients have good oral hygiene.
Systemic healthy individuals ,Age more than18 years.
Healed edentulous area for at least 6 months after tooth extraction (delayed implant protocol).
Patients have at least two missing teeth in the jaw (canine to 1st molar area) indicated for the dental implant.

Exclusion criteria

Presence of systemic diseases preventing implantation.
Previous implantation or augmentation of the same region.
The need for additional bone augmentation procedures (such as maxillary sinus augmentation)
Partial or total edentulous ridge associated with a severe knife-edge ridge .
Acute infection or any pathological lesion a the implant site.
Allergy to one of the materials to be used during operation.
Pregnancy.
Radiation therapy, bisphosphonate drugs , Osteoradionecrosis.