Effect of Red and Blue Light Irradiation on Postoperative Wound Healing in Perianal Absces

The Affiliated Hospital of Putian University

Status: Not yet enrolling

Conditions: Perianal Abscess

Treatments: Device: Red-blue light exposure; Device: Red light exposure

Study type: Interventional

Funder types: Other

Identifiers

NCT07155356

AHPutianU-012

Details and patient eligibility

About

This study aims to investigate whether specialized red-blue light irradiation facilitates faster postoperative recovery and reduces complication rates in patients following perianal abscess surgery. A total of 222 eligible patients were randomly allocated equally into three groups (74 per group):①Routine Care Group: Standard wound care including cleansing and dressing changes；②Red Light Therapy Group: Routine care plus red light phototherapy；③Combined Red-Blue Light Therapy Group: Routine care plus concurrent red and blue light phototherapy.Wound healing time and incidence of complications were compared to assess postoperative recovery across interventions. The primary hypothesis posits that adjunctive phototherapy-particularly combined red-blue light irradiation-will significantly enhance wound healing, reduce edema and pain, and decrease complication rates (e.g.bleeding, urinary retention) compared to routine care alone.

Enrollment: 222 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Aged between 18 and 75 years;
• Clinical diagnosis of perianal abscess；
• Procedure: Radical resection with incision and drainage.

Exclusion criteria

• Concurrent anorectal disorders (hemorrhoids, anal fissure) or malignancies/infectious diseases；
• History of psychiatric disorders；
• Analgesic use within 7 days preoperatively；
• Coagulopathy or cardiac/hepatic dysfunction；
• Pregnancy or lactation；
• Contraindications to phototherapy；
• IBD-related perianal abscess.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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222 participants in 3 patient groups

control group

No Intervention group

Description:

Routine care of patients after surgery for perianal abscesses.

Red Ligh Group

Experimental group

Description:

Postoperative care of patients with perianal abscesses using routine plus red light irradiation.

Treatment:

Device: Red light exposure

Combined Red-Blue Light Group

Experimental group

Description:

Use of routine plus red and blue light in postoperative care of patients with perianal abscesses.

Treatment:

Device: Red-blue light exposure