Effect of Red and Blue Light Irradiation on Wound Healing After Hemorrhoid Surgery

The Affiliated Hospital of Putian University

Status: Not yet enrolling

Conditions: Hemorrhoids

Treatments: Device: Red light exposure; Device: Red-blue light exposure

Study type: Interventional

Funder types: Other

Identifiers

NCT07121686

AHPutianU 2024212-1

Details and patient eligibility

About

The subjects of this study were patients who took mixed haemorrhoidectomy during the period of December 2024 - December 2025 . The haemorrhoidectomy patients were randomly divided into routine group, red light group and red and blue light group, and were given different ways of trauma care, and the number of cases in each group was 105 , with a total of 305 cases. Observe the difference between red and blue light irradiation and routine care on the healing time of postoperative trauma and postoperative complications after haemorrhoidectomy, and evaluate the patients' quality of life and satisfaction with treatment under both red light irradiation and routine care.

Full description

The subjects of this study were patients who took mixed haemorrhoidectomy during the period of December 2024 - December 2025 . The diagnostic criteria were haemorrhoidal disease diagnosed as degree III-IV according to Goligher's classification. Inclusion criteria were 18 years < age < 75 years; diagnosis of haemorrhoids; internal haemorrhoid ligation + external haemorrhoidectomy. Exclusion criteria were patients with psychiatric disorders; patients with chronic diseases such as diabetes mellitus, hypertension and coronary artery disease; patients who underwent other treatments in addition to haemorrhoidectomy such as haemorrhoidal radiofrequency ablation/ sclerotherapy; patients who were unable to cooperate with the follow-up; and patients with perianal abscess, anal fissure, anal fistulae, and anorectal papillae hypertrophy. The haemorrhoidectomy patients were randomly divided into the conventional group, the red light group and the red and blue light group, and were given different ways of trauma care, and the number of cases in each group was 105 , with a total of 305 cases. The control group was given routine potassium permanganate sitz bath and routine care after internal haemorrhoid ligation + external haemorrhoidectomy to encourage patients to carry out functional exercise in moderation, mainly for anal lifting, buttock lifting and abdominal massage, etc.; the red light group was based on the control group, using red light irradiation for traumatic treatment; the red and blue light group was based on the control group, using red and blue light irradiation for traumatic treatment. Observe the difference between red and blue light irradiation and routine care on the healing time of postoperative trauma and postoperative complications after haemorrhoid surgery, and evaluate the patients' quality of life and satisfaction with treatment under both red light irradiation and routine care. Specific research content is to collect the postoperative data of the three groups of patients, including the recording of surgery-related pain scores, respectively, before the red light intervention and after the intervention of 1 d, 2 d, 3 d, 5 d, 7 d using visual analogue scoring (VAS) to assess the intensity of the patient's pain; the recording of the length of hospital stay; the recording of the degree of oedema of the anal verge were assessed before the red light intervention and after the intervention of 1 d, 2 d, 3 d, 5 d, 7 d, respectively, 0 Score 0: no oedema or slight oedema on the wound, but no impact on life. Score 2: oedema is present in only one area of the wound and is less than 1 cm in diameter, affecting daily activities. 4 points: multiple oedemas with a diameter of 1-2 cm, affecting daily activities. 6 points: multiple oedemas with a diameter of more than 2 cm, seriously affecting daily activities; follow up on the time to complete healing of the wound, quality of life scores, and the patient's satisfaction with the treatment.

Enrollment: 315 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Aged 18-75 years
• Diagnosed with Grade III-IV hemorrhoids according to Goligher classification
• Scheduled to undergo rubber band ligation of internal hemorrhoids + external hemorrhoidectomy
• Willing and able to provide written informed consent
• Able to comply with postoperative follow-up and treatment protocol

Exclusion criteria

• Psychiatric disorders or cognitive impairment
• Uncontrolled chronic diseases:
• Diabetes (HbA1c >7.5%)
• Hypertension (BP >160/100 mmHg)
• Coronary artery disease (NYHA Class III-IV heart failure)
• Concurrent other hemorrhoid treatments (e.g., radiofrequency ablation/sclerotherapy)
• Inability to complete follow-up (e.g., living too far away, no stable contact)
• Concurrent anal disorders:
• Perianal abscess
• Anal fissure
• Anal fistula
• Hypertrophied anal papilla
• Pregnancy or lactation (for female patients)
• History of phototherapy allergy
• Participation in other clinical trials within 3 months

For registration, simply copy this structured list directly into the PRS system's eligibility section. The clear formatting will facilitate efficient review.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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315 participants in 3 patient groups

Conventional Care Group

No Intervention group

Description:

Standard postoperative care for hemorrhoidectomy patients.

Red Light Therapy Group

Experimental group

Description:

Conventional care plus red light phototherapy.

Treatment:

Device: Red light exposure

Red-Blue Light Therapy Group

Experimental group

Description:

Conventional care plus combined red-blue light phototherapy.

Treatment:

Device: Red-blue light exposure