Effect of Repeated Removal and Re-placement of Abutments Around Dental Implants

U

University of Roma La Sapienza

Status

Unknown

Conditions

Peri-implant Mucositis

Treatments

Diagnostic Test: Repeated removal and re-placement of healing and prosthetic abutments

Study type

Interventional

Funder types

Other

Identifiers

NCT04415801
3/20

Details and patient eligibility

About

Repeated removal and re-placement of healing and prosthetic abutments result in frequent injuries to the soft tissues. The purpose was to evaluate the effect of repeated removal and re-placement of laser microgrooved and smooth/machined healing and prosthetic abutments during restorative stages, and 1 year after functional loading, on proinflammatory cytokine levels around dental implants.

Full description

Twenty-four patients each received 2 one-stage implants in a split mouth design on the same jaw. In each patient one healing and prosthetic abutments with a laser microgrooved surface (LMS group) and one healing and prosthetic abutments with smooth/machined surface (S/MS group) were used. Four months following implant placement [Baseline (BSL)], the healing abutments were disconnnected and reconnected three times to carry out the impression procedures and metal framework try-in. Four weeks later (T0), definitive prosthetic abutments were installated with screw retained crowns. Samples for immunological analyses were taken from the sulcus around each implant at BSL, T0, and 1 year after functional loading (T1). Peri-implant crevicular fluid samples were analyzed for interleukin-1beta (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor (TNF)-α levels using the ELISA kit.

Enrollment

20 estimated patients

Sex

All

Ages

18 to 70 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • 18 years or older, in good general health, and with sufficient amount of bone available to place a standard implant

Exclusion criteria

  • natural teeth adjacent to surgical area affected by untreated periodontal or endodontic infections, peri-implant bone defects requiring bone augmentation, absence of opposing occlusion,

Trial design

20 participants in 1 patient group

Implant abutments
Experimental group
Description:
implant abutments
Treatment:
Diagnostic Test: Repeated removal and re-placement of healing and prosthetic abutments

Trial contacts and locations

1

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Central trial contact

Renzo Guarnieri, MD DDS; Renzo Guarnieri

Data sourced from clinicaltrials.gov

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