Effect of Replacing Buried Sutures With Tissue Adhesive on Aesthetic Outcome of Surgical Wounds.

West Virginia University

Status: Terminated

Conditions: Surgical Wound

Treatments: Procedure: Closure of surgical wounds using buried sutures or tissue adhesive on aesthetic outcome.

Study type: Interventional

Funder types: Other

Identifiers

NCT03425370

1710792979

Details and patient eligibility

About

Surgery wounds are typically closed with combination of absorbable stitches placed under the skin and non-absorbable stitched placed at the skin surface. Absorbable sutures can produce unwanted side effects when the body produces a reaction to them. The investigators are conducting a study to determine if absorbable stitches can be replaced but tissue glue applied on the surface of the skin. If participants enroll in the study, the investigators will close one half of the participants wound with absorbable stitches placed under the skin and non-absorbable stitches on the surface. The other half of the wound will be closed with non-absorbable stitches and tissue glue. The appearance of the scar (if any) will then be evaluated at 3- and 6-month follow-ups by two dermatologists (either board-certified dermatologists or dermatology residents) and the patient.

Enrollment: 10 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age 18 years or older
• Postoperative defects of at least 3 cm, resulting from either Mohs micrographic surgery or surgical excision
• Willing to give informed consent and return for follow-up visits 3 months and 6 months following surgery

Exclusion criteria

• Pregnant
• Unable to understand English
• Mentally impaired
• Incarcerated
• Has nonlinear closures

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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10 participants in 2 patient groups

Wound Side A: buried sutures, Wound Side B: tissue adhesive

Experimental group

Description:

Wounds halves will be labeled as A (left/superior) or B (right/inferior), the halves will be randomized to receive either tissue glue or deep sutures.

Treatment:

Procedure: Closure of surgical wounds using buried sutures or tissue adhesive on aesthetic outcome.

Wound Side A: tissue adhesive, Wound Side B: buried sutures

Experimental group

Description:

Wounds halves will be labeled as A (left/superior) or B (right/inferior), the halves will be randomized to receive either tissue glue or deep sutures.

Treatment:

Procedure: Closure of surgical wounds using buried sutures or tissue adhesive on aesthetic outcome.