Effect of Retrograde Autologous Blood Priming on Pulmonary Mechanics in Pediatric Cardiac Surgery (RAPCPB)

Ain Shams University

Status: Completed

Conditions: Congenital Heart Disease

Treatments: Procedure: Pediatric cardiac surgery

Study type: Interventional

Funder types: Other

Identifiers

NCT04260204

ACTS004367

Details and patient eligibility

About

The present study hypothesized that beyond its hemodynamic affects,retrograde autologus blood priming of cardiopulmonary bypass (RAP) has a positive impact on hemodynamics and pulmonary mechanics subjected to cardiac surgery.

Full description

This prospective randomized study analyzed the clinical records of 124 children subjected to cardiac surgery for congenital heart diseases with left to right shunt. They comprised 64 patients with RAP and 60 patients conventional cardiopulmonary bypass priming. The preoperative, intraoperative and postoperative data of the studied patients were reported.

Enrollment: 124 patients

Sex: All

Ages: 12 months to 5 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• children complained of congenital heart disease with left to right shunt pressure or volume load

Exclusion criteria

• cyanotic heart disease

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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124 participants in 2 patient groups

Retrograde priming

Active Comparator group

Description:

retrograde autologous Blood Priming of Cardiopulmonary Bypass (RAP) in young children subjected to cardiac surgery for congenital heart defects with left to right shunt associated with volume or pressure overload.

Treatment:

Procedure: Pediatric cardiac surgery

conventional priming

Active Comparator group

Description:

conventional cardiopulmonary priming in young children subjected to cardiac surgery for congenital heart defects with left to right shunt associated with volume or pressure overload.

Treatment:

Procedure: Pediatric cardiac surgery